diff --git a/packages/reflex-base/news/6740.bugfix.md b/packages/reflex-base/news/6740.bugfix.md
new file mode 100644
index 00000000000..a176841db94
--- /dev/null
+++ b/packages/reflex-base/news/6740.bugfix.md
@@ -0,0 +1 @@
+Use monotonic time for computed var update intervals so system clock changes do not cause early or delayed cache refreshes.
diff --git a/packages/reflex-base/src/reflex_base/vars/base.py b/packages/reflex-base/src/reflex_base/vars/base.py
index d9a3f939a27..05570d862b9 100644
--- a/packages/reflex-base/src/reflex_base/vars/base.py
+++ b/packages/reflex-base/src/reflex_base/vars/base.py
@@ -11,6 +11,7 @@
 import json
 import re
 import string
+import time
 import uuid
 import warnings
 from abc import ABCMeta
@@ -91,6 +92,7 @@
 warnings.filterwarnings("ignore", message="fields may not start with an underscore")
 
 _PYDANTIC_VALIDATE_VALUES = "__pydantic_validate_values__"
+_MONOTONIC_CLOCK_ID = uuid.uuid4()
 
 
 def _pydantic_validator(*args, **kwargs):
@@ -2488,9 +2490,14 @@ def needs_update(self, instance: BaseState) -> bool:
         if self._update_interval is None:
             return False
         last_updated = getattr(instance, self._last_updated_attr, None)
-        if last_updated is None:
+        if (
+            not isinstance(last_updated, tuple)
+            or len(last_updated) != 2
+            or last_updated[0] != _MONOTONIC_CLOCK_ID
+        ):
             return True
-        return datetime.datetime.now() - last_updated > self._update_interval
+        elapsed = time.monotonic() - last_updated[1]
+        return elapsed < 0 or elapsed > self._update_interval.total_seconds()
 
     @overload
     def __get__(
@@ -2594,7 +2601,11 @@ def __get__(self, instance: BaseState | None, owner: type):
                 # Ensure the computed var gets serialized to redis.
                 instance._was_touched = True
                 # Set the last updated timestamp on the state instance.
-                setattr(instance, self._last_updated_attr, datetime.datetime.now())
+                setattr(
+                    instance,
+                    self._last_updated_attr,
+                    (_MONOTONIC_CLOCK_ID, time.monotonic()),
+                )
             value = getattr(instance, self._cache_attr)
 
         self._check_deprecated_return_type(instance, value)
@@ -2856,7 +2867,11 @@ async def _awaitable_result(instance: BaseState = instance) -> RETURN_TYPE:
                 # Ensure the computed var gets serialized to redis.
                 instance._was_touched = True
                 # Set the last updated timestamp on the state instance.
-                setattr(instance, self._last_updated_attr, datetime.datetime.now())
+                setattr(
+                    instance,
+                    self._last_updated_attr,
+                    (_MONOTONIC_CLOCK_ID, time.monotonic()),
+                )
             value = getattr(instance, self._cache_attr)
             self._check_deprecated_return_type(instance, value)
             return value
diff --git a/tests/units/vars/test_base.py b/tests/units/vars/test_base.py
index e4d7e363e3c..eb210e8f396 100644
--- a/tests/units/vars/test_base.py
+++ b/tests/units/vars/test_base.py
@@ -1,6 +1,8 @@
+import datetime
 from collections.abc import Mapping, Sequence
 
 import pytest
+from pytest_mock import MockerFixture
 from reflex_base.vars.base import computed_var, figure_out_type
 
 from reflex.state import State
@@ -77,3 +79,100 @@ def cv(self) -> int:
 
     replaced = cv._replace(_var_type=float)
     assert replaced._var_type is float
+
+
+@pytest.mark.parametrize("is_async", [False, True])
+@pytest.mark.parametrize(
+    ("wall_clock_delta", "monotonic_delta", "expected_value"),
+    [
+        (datetime.timedelta(hours=-1), 11, 2),
+        (datetime.timedelta(hours=1), 1, 1),
+    ],
+)
+@pytest.mark.asyncio
+async def test_computed_var_interval_uses_monotonic_time(
+    mocker: MockerFixture,
+    is_async: bool,
+    wall_clock_delta: datetime.timedelta,
+    monotonic_delta: int,
+    expected_value: int,
+) -> None:
+    """Test interval expiry is unaffected by wall-clock changes.
+
+    Args:
+        mocker: Pytest mock fixture.
+        is_async: Whether to access the asynchronous computed var.
+        wall_clock_delta: The wall-clock change after the initial access.
+        monotonic_delta: The elapsed monotonic time after the initial access.
+        expected_value: The expected computed value after the clocks advance.
+    """
+    call_count = 0
+
+    class StateTest(State):
+        @computed_var(cache=True, interval=10)
+        def cv(self) -> int:
+            nonlocal call_count
+            call_count += 1
+            return call_count
+
+        @computed_var(cache=True, interval=10)
+        async def async_cv(self) -> int:
+            nonlocal call_count
+            call_count += 1
+            return call_count
+
+    monotonic_time = 100
+    mocker.patch(
+        "reflex_base.vars.base.time.monotonic", side_effect=lambda: monotonic_time
+    )
+    initial_wall_time = datetime.datetime(2026, 1, 1)
+    datetime_mock = mocker.patch("reflex_base.vars.base.datetime.datetime")
+    datetime_mock.now.return_value = initial_wall_time
+
+    state = StateTest()
+    if is_async:
+        assert await state.async_cv == 1
+    else:
+        assert state.cv == 1
+
+    monotonic_time += monotonic_delta
+    datetime_mock.now.return_value = initial_wall_time + wall_clock_delta
+
+    if is_async:
+        assert await state.async_cv == expected_value
+    else:
+        assert state.cv == expected_value
+    assert call_count == expected_value
+
+
+@pytest.mark.parametrize(
+    "persisted_timestamp",
+    [
+        datetime.datetime(2026, 1, 1),
+        (object(), 100),
+    ],
+)
+def test_computed_var_interval_expires_incompatible_timestamp(
+    persisted_timestamp: object,
+) -> None:
+    """Test an interval cache with an incompatible timestamp is expired.
+
+    Args:
+        persisted_timestamp: A timestamp from a legacy version or another clock.
+    """
+    call_count = 0
+
+    class StateTest(State):
+        @computed_var(cache=True, interval=10)
+        def cv(self) -> int:
+            nonlocal call_count
+            call_count += 1
+            return call_count
+
+    state = StateTest()
+    assert state.cv == 1
+
+    computed = StateTest.computed_vars["cv"]
+    setattr(state, computed._last_updated_attr, persisted_timestamp)
+
+    assert state.cv == 2